MAN2A2 Antibody

• Background:

  MAN2A2 catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.

• NCBI Gene ID:

  4122

• Swiss Prot:

  P49641

• Accession Number:

  P49641

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This MAN2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-796 amino acids from the Central region of human MAN2A2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  131 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MAN2A2

• NCBI Official Name:

  Alpha-mannosidase 2x

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lesch, K.P., et al.Neural Transm 115 (11) :1573-1585 (2008)

• Background Reference 02:

  Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

• Background Reference 03:

  Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :

• Background Reference 04:

  Misago, M., et al. Proc. Natl. Acad. Sci. U.S.A. 92 (25) :11766-11770 (1995)

• Other Product Names:

  Alpha-mannosidase 2x, Alpha-mannosidase IIx, Man IIx, Mannosidase alpha class 2A member 2, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN2A2, MANA2X

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  347595795

• Physical Properties:

  Liquid