MAN2A2 Antibody

• Background :

  MAN2A2 catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.

• NCBI Gene ID :

  4122

• Swiss Prot :

  P49641

• Accession Number :

  P49641

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This MAN2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-796 amino acids from the Central region of human MAN2A2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  131 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  MAN2A2

• NCBI Official Name :

  Alpha-mannosidase 2x

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lesch, K.P., et al.Neural Transm 115 (11) :1573-1585 (2008)

• Background Reference 02 :

  Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

• Background Reference 03 :

  Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :

• Background Reference 04 :

  Misago, M., et al. Proc. Natl. Acad. Sci. U.S.A. 92 (25) :11766-11770 (1995)

• Other Product Names :

  Alpha-mannosidase 2x, Alpha-mannosidase IIx, Man IIx, Mannosidase alpha class 2A member 2, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN2A2, MANA2X

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  347595795

• Physical Properties :

  Liquid