SRC1 Antibody

CAT: 0223-56-307Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-307Size:400 µL
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Background
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
8648
Swiss Prot
Q15788
Accession Number
Q15788
Host
Rabbit
Reactivity
Human
Immunogen
This SRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-625 amino acids from the Central region of human SRC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
157 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NCOA1
NCBI Official Name
Nuclear receptor coactivator 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Son, Y.L., et al. FEBS Lett. 584 (18) :3862-3866 (2010)
Background Reference 03
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 04
McIlroy, M., et al. Cancer Res. 70 (4) :1585-1594 (2010)
Other Product Names
Nuclear receptor coactivator 1, NCoA-1, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1, SRC-1, NCOA1, BHLHE74, SRC1
Tested Applications
WB
Protein ID
158518533
Physical Properties
Liquid

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