CFD Antibody

CAT: 0223-56-222Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-222Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
NCBI Gene ID
1675
Swiss Prot
P00746
Accession Number
P00746
Host
Rabbit
Reactivity
Human
Immunogen
This CFD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-99 amino acids from the N-terminal region of human CFD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit IgG
Applications Notes
For WB starting dilution is: 1:2000
Symbol
CFD
NCBI Official Name
Complement factor D
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Hietaharju, A., et al. Eur. J. Neurol. 17 (2) :332-334 (2010)
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Ciprandi, G., et al. Int. Immunopharmacol. 9 (12) :1460-1463 (2009)
Other Product Names
Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD
Tested Applications
WB, IHC-P
Protein ID
158515408
Physical Properties
Liquid

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