Products for Research Use Only
RegisterLogin

BMPR1B Antibody

CAT: 0223-56-190Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-190Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.
NCBI Gene ID
658
Swiss Prot
O00238
Accession Number
O00238
Host
Rabbit
Reactivity
Human
Immunogen
This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human BMPR1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
BMPR1B
NCBI Official Name
Bone morphogenetic protein receptor type-1B
NCBI Organism
Homo sapiens
Background Reference 01
Mick, E., et al.Am Acad Child Adolesc Psychiatry 49 (9) :898-905 (2010)
Background Reference 02
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)
Background Reference 03
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 04
Ma, Y., et al. J. Exp. Clin. Cancer Res. 29, 85 (2010) :
Other Product Names
Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, CDw293, BMPR1B
Tested Applications
WB, IHC-P
Physical Properties
Liquid

Related Products

CatalogName
60-841BMPR1A Antibody
45-334BMPR1A Antibody
60-842BMPR1A Antibody
60-840BMPR1A Antibody
60-839BMPR1A Antibody
58-516Mouse Bmpr1a Antibody
60-854BMPR2 Antibody
6909-002mgBMP15 Antibody
6909-01BMP15 Antibody
15-829BMP10 Antibody

Alternative Products

CatalogName
DF6748-01BMPR1B Antibody

Popular Products