TBCA Antibody

• Background :

  The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.

• NCBI Gene ID :

  6902

• Swiss Prot :

  O75347

• Accession Number :

  O75347

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the Central region of human TBCA.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  13 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  TBCA

• NCBI Official Name :

  Tubulin-specific chaperone A

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02 :

  Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

• Background Reference 03 :

  Bruneel, A., et al. Proteomics 5 (15) :3876-3884 (2005)

• Background Reference 04 :

  Nolasco, S., et al. FEBS Lett. 579 (17) :3515-3524 (2005)

• Other Product Names :

  Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA

• Tested Applications :

  WB, IHC-P

• Physical Properties :

  Liquid