TBCE Antibody

• Background :

  Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

• NCBI Gene ID :

  6905

• Swiss Prot :

  Q15813

• Accession Number :

  Q15813

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  59 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  TBCE

• NCBI Official Name :

  Tubulin-specific chaperone E

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Biernacki, M.A., et al. Cancer Res. 70 (3) :906-915 (2010)

• Background Reference 02 :

  Padidela, R., et al. J. Clin. Endocrinol. Metab. 94 (8) :2686-2691 (2009)

• Background Reference 03 :

  Lindgren, C.M., et al. PLoS Genet. (6), E1000508 (2009)

• Background Reference 04 :

  Jin, S., et al. Development 136 (9) :1571-1581 (2009)

• Other Product Names :

  Tubulin-specific chaperone E, Tubulin-folding cofactor E, TBCE

• Tested Applications :

  WB

• Protein ID :

  74762146

• Physical Properties :

  Liquid