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TBCE Antibody

CAT: 0223-64-058Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-64-058Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
NCBI Gene ID
6905
Swiss Prot
Q15813
Accession Number
Q15813
Host
Rabbit
Reactivity
Human
Immunogen
This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TBCE
NCBI Official Name
Tubulin-specific chaperone E
NCBI Organism
Homo sapiens
Background Reference 01
Biernacki, M.A., et al. Cancer Res. 70 (3) :906-915 (2010)
Background Reference 02
Padidela, R., et al. J. Clin. Endocrinol. Metab. 94 (8) :2686-2691 (2009)
Background Reference 03
Lindgren, C.M., et al. PLoS Genet. (6), E1000508 (2009)
Background Reference 04
Jin, S., et al. Development 136 (9) :1571-1581 (2009)
Other Product Names
Tubulin-specific chaperone E, Tubulin-folding cofactor E, TBCE
Tested Applications
WB
Protein ID
74762146
Physical Properties
Liquid

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