RegisterLogin

SET07 Antibody

CAT: 0223-56-115Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-115Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.
NCBI Gene ID
387893
Swiss Prot
Q9NQR1
Accession Number
Q9NQR1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SET07 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-53 amino acids from the N-terminal region of human SET07.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
SETD8
NCBI Official Name
N-lysine methyltransferase SETD8
NCBI Organism
Homo sapiens
Background Reference 01
Nishioka, K., et al., Mol. Cell 9 (6) :1201-1213 (2002) .
Background Reference 02
Fang, J., et al., Curr. Biol. 12 (13) :1086-1099 (2002) .
Other Product Names
N-lysine methyltransferase SETD8, 211-, H4-K20-HMTase SETD8, Histone-lysine N-methyltransferase SETD8, Lysine N-methyltransferase 5A, PR/SET domain-containing protein 07, PR-Set7, PR/SET07, SET domain-containing protein 8, SETD8, KMT5A, PRSET7, SET07, SET8
Tested Applications
WB, IHC-P
Protein ID
25091219
Physical Properties
Liquid

Related Products

CatalogName
70-595SETD7 / SET7 Antibody
30-476SETD7 Antibody
56-133SET7 Antibody
56-134SET7 Antibody
24-013SETD7 Antibody, KO Validated
24-854SETD7 Antibody [RAB-C220], Rabbit IgG
24-853SETD7 Antibody [RAB-C220], Human Fab fragment
64-160WAS Antibody
13-349WAS Antibody
60-596WAS Antibody

Alternative Products

CatalogName
AM1191aSET07 Antibody
F40199-0.4MLSET07 Antibody / KMT5A
AMM22168G-01SET07 Antibody [AMM22168G]
A-3013-050SET07 Polyclonal Antibody
AMM22100G-01SET07 Antibody [AMM22100G]
AMM22099G-01SET07 Antibody [AMM22099G]
M05349-1-80ulAnti-SET07 Antibody
E10G30048SET07 Rabbit Polyclonal Antibody
E45R30866G-1SET07 Antibody (C-term)
AMM86128-01SET07 Mouse Monoclonal Antibody

Popular Products