COL4A3 Antibody

• Background:

  Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.

• NCBI Gene ID:

  1285

• Swiss Prot:

  Q01955

• Accession Number:

  Q01955

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COL4A3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 141-173 amino acids from human COL4A3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Signal Transduction, Stem Cell

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  162 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  COL4A3

• NCBI Official Name:

  Collagen alpha-3 (IV) chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mariyama M., et al.J. Biol. Chem. 269:23013-23017 (1994) .

• Background Reference 02:

  Leinonen A., et al.Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.

• Background Reference 03:

  Heidet L., et al.J. Am. Soc. Nephrol. 12:97-106 (2001) .

• Background Reference 04:

  Hillier L.W., et al.Nature 434:724-731 (2005) .

• Other Product Names:

  Collagen alpha-3 (IV) chain, Goodpasture antigen, Tumstatin, COL4A3

• Tested Applications:

  WB

• Protein ID:

  134035067

• Physical Properties:

  Liquid