GRIN2A Antibody

CAT: 0223-55-818Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-818Size:400 µL
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Background
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2903
Swiss Prot
Q12879
Accession Number
Q12879
Host
Rabbit
Reactivity
Human
Immunogen
This GRIN2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1291-1318 amino acids from the C-terminal region of human GRIN2A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
165 kDa
Fragment
Rabbit Ig
Symbol
GRIN2A
NCBI Official Name
Glutamate receptor ionotropic, NMDA 2A
NCBI Organism
Homo sapiens
Background Reference 01
Endele, S., et al. Nat. Genet. 42 (11) :1021-1026 (2010)
Background Reference 02
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 03
Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)
Background Reference 04
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Other Product Names
Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2A, NMDAR2A
Tested Applications
WB, IHC-P, Flow
Protein ID
14285603
Physical Properties
Liquid

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