GRIN2C Antibody

• Background:

  N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) .

• NCBI Gene ID:

  2905

• Swiss Prot:

  Q14957

• Accession Number:

  NP_000826

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRIN2C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GRIN2C antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  136 kDa

• Applications Notes:

  GRIN2C antibody can be used for detection of GRIN2C by ELISA at 1:62500. GRIN2C antibody can be used for detection of GRIN2C by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  GRIN2C

• NCBI Official Name:

  Glutamate receptor, ionotropic, N-methyl D-aspartate 2C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Self, R.L., et al., (2004) Brain Res. 995 (1), 39-45.

• Other Product Names:

  GRIN2C, NR2C, GluN2C, NMDAR2C

• Tested Applications:

  ELISA, WB

• Protein ID:

  55770854

• Physical Properties:

  Liquid