GRIN2B Antibody

• Background:

  N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B) . The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

• NCBI Gene ID:

  2904

• Swiss Prot:

  Q13224

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1400 to the C-terminus of human GRIN2B (NP_000825.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 181kDa

• Fragment:

  IgG

• Symbol:

  GRIN2B

• NCBI Official Name:

  Glutamate receptor, ionotropic, N-methyl D-aspartate 2B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GRIN2B, glutamate receptor, ionotropic, N-methyl D-aspartate 2B, HGNC:4586, NMDAR2B, NR2B, hNR3, N-methyl-D-aspartate receptor subunit 2B

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid