GRIN2C Antibody

• Background:

  N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) . [provided by RefSeq].

• NCBI Gene ID:

  2905

• Swiss Prot:

  Q14957

• Accession Number:

  Q14957

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  134 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GRIN2C

• NCBI Official Name:

  Glutamate receptor ionotropic, NMDA 2C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)

• Background Reference 02:

  Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :

• Background Reference 03:

  Shi, J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (7), 1270-1277 (2008) :

• Background Reference 04:

  Self, R.L., et al. Brain Res. 995 (1) :39-45 (2004)

• Other Product Names:

  Glutamate receptor ionotropic, NMDA 2C, GluN2C, Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C, GRIN2C, NMDAR2C

• Tested Applications:

  WB

• Protein ID:

  313104210

• Physical Properties:

  Liquid