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GRIN2C Antibody

CAT: 0223-60-708Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-708Size:400 µL
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Background
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) . [provided by RefSeq].
NCBI Gene ID
2905
Swiss Prot
Q14957
Accession Number
Q14957
Host
Rabbit
Reactivity
Mouse
Immunogen
This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
134 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GRIN2C
NCBI Official Name
Glutamate receptor ionotropic, NMDA 2C
NCBI Organism
Homo sapiens
Background Reference 01
Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)
Background Reference 02
Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
Background Reference 03
Shi, J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (7), 1270-1277 (2008) :
Background Reference 04
Self, R.L., et al. Brain Res. 995 (1) :39-45 (2004)
Other Product Names
Glutamate receptor ionotropic, NMDA 2C, GluN2C, Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C, GRIN2C, NMDAR2C
Tested Applications
WB
Protein ID
313104210
Physical Properties
Liquid

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