GIGYF1 Antibody

• Background:

  May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity) .

• NCBI Gene ID:

  64599

• Swiss Prot:

  O75420

• Accession Number:

  O75420

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GIGYF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-694 amino acids from the Central region of human GIGYF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  115 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GIGYF1

• NCBI Official Name:

  PERQ amino acid-rich with GYF domain-containing protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Szafranski, K., et al. Genome Biol. (8), R154 (2007) :

• Background Reference 02:

  Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

• Background Reference 03:

  Giovannone, B., et al. J. Biol. Chem. 278 (34) :31564-31573 (2003)

• Background Reference 04:

  Wilson, M.D., et al. Nucleic Acids Res. 29 (6) :1352-1365 (2001)

• Other Product Names:

  PERQ amino acid-rich with GYF domain-containing protein 1, GRB10-interacting GYF protein 1, GIGYF1, CDS2, PERQ1

• Tested Applications:

  WB

• Physical Properties:

  Liquid