MDM2 Antibody

• NCBI Gene ID:

  4193

• Swiss Prot:

  Q00987

• Accession Number:

  NP_002383.2

• Host:

  Goat

• Reactivity:

  Human

• Immunogen:

  The immunogen for this antibody is: C-DELSGERQRKRHKSD

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

• Positive Control:

  Cat. No. 1304 - Human Liver Tissue Lysate

• Concentration:

  500 ug/mL

• Homology:

  Expected Species Reactivity based on sequence homology: Rat, Cat, Dog, Pig, Cow

• Buffer:

  Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and store at -20˚ C. Minimize freezing and thawing.

• Specificity:

  This antibody is expected to recognize isoform MDM2 (NP_002383.2) only.

• Applications Notes:

  Peptide ELISA: Western Blot:

• Symbol:

  MDM2

• NCBI Official Name:

  MDM2 oncogene, E3 ubiquitin protein ligase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bond GL, Hu W, Bond EE, Robins H, Lutzker SG, Arva NC, Bargonetti J, Bartel F, Taubert H, Wuerl P, Onel K, Yip L, Hwang SJ, Strong LC, Lozano G, Levine AJ. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell. 2004 Nov 24;119 (5) :591-602.

• Other Product Names:

  MDM2, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse), HGNC:6973, MGC71221, hdm2, mouse double minute 2 homolog, mouse double minute 2, human homolog of, p53-binding protein, p53-binding protein MDM2, ubiquitin-protein ligase E3 Mdm2, Mdm2 p53 binding protein homolog (mouse), HDMX, MGC5370, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein, OTTHUMP00000183495, double minute 2, human homolog of

• Tested Applications:

  ELISA, WB

• Protein ID:

  89993689

• Physical Properties:

  Liquid