HMGCR Antibody

• NCBI Gene ID:

  3156

• Swiss Prot:

  P04035

• Accession Number:

  NP_000850.1

• Host:

  Goat

• Immunogen:

  The immunogen for this antibody is: C-ADPSPQNSTADTSK

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction, Cancer

• Purification:

  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

• Concentration:

  500 ug/mL

• Homology:

  Expected Species Reactivity based on sequence homology: Human

• Buffer:

  Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and store at -20˚ C. Minimize freezing and thawing.

• Applications Notes:

  Peptide ELISA: Western Blot:

• Symbol:

  HMGCR

• NCBI Official Name:

  3-hydroxy-3-methylglutaryl-CoA reductase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH. The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. J Clin Invest. 2007 Dec;117 (12) :3940-51.

• Other Product Names:

  HMGCR, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase, LDLCQ3, 3-hydroxy-3-methylglutaryl CoA reductase (NADPH), hydroxymethylglutaryl-CoA reductase, HMG-CoA reductase

• Tested Applications:

  ELISA

• Protein ID:

  4557643

• Physical Properties:

  Liquid