IL-21 Antibody (biotin)

• Background:

  A novel cytokine related to IL2 and IL15 was recently identified and designated IL21. IL21 has been found to be a powerful growth factor for naive B cells. The receptor for IL21 (IL21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL21 signaling. Both IL21R and the gc are necessary for the IL21 function. IL21 and its receptor activate JAKSTAT signaling pathway. IL21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL21 plays a role in the proliferation and maturation of NK, B and T cell populations.

• NCBI Gene ID:

  59067

• Swiss Prot:

  Q9HBE4

• Accession Number:

  Q9HBE4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-21. Human IL-21 specific antibody was purified by affinity chromatography and then biotinylated.

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Primary Antibodies, Antibody Pairs

• Field of Research:

  Immunology, Chemokines & Cytokines

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  IL-21 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  IL21

• NCBI Official Name:

  Interleukin 21

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Za11, IL-21Interleukin-21, Za11, IL-21

• Tested Applications:

  ELISA, WB

• Protein ID:

  55976599

• Physical Properties:

  Lyophilized