IL-21 Antibody

• Background:

  A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.

• NCBI Gene ID:

  60505

• Swiss Prot:

  Q9ES17

• Accession Number:

  Q9ES17

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIL-21 (Murine Interleukin-21) . Murine IL-21 specific antibody was purified by affinity chromatography employing immobilized mIL-21 matrix.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Antibody Pairs

• Field of Research:

  Immunology, Chemokines & Cytokines

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  IL-21 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  Il21

• NCBI Official Name:

  Interleukin 21

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Interleukin-21IL-21

• Tested Applications:

  ELISA, WB

• Protein ID:

  55976590

• Physical Properties:

  Lyophilized