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Il-21 Antibody

CAT: 0800-RQ6191Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6191Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9ES17
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A mouse recombinant partial protein (amino acids H18-S146) was used as the immunogen for the Il-21 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.0125% sodium azide
Reconstitution
After reconstitution, the Il-21 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Il-21 antibody is available for research use only.
Storage Conditions
After reconstitution, the Il-21 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Il-21 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE rat spleen with Il-21 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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