ETS1 Antibody

• Background:

  ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (summary by Dwyer et al., 2007 [PubMed 17986575]) .

• NCBI Gene ID:

  2113

• Swiss Prot:

  P14921

• Accession Number:

  P14921

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ETS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human ETS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit IgG

• Symbol:

  ETS1

• NCBI Official Name:

  Protein C-ets-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Harris, T.A., et al. Arterioscler. Thromb. Vasc. Biol. 30 (10) :1990-1997 (2010) He, C.F., et al. Lupus 19 (10) :1181-1186 (2010) Russell, L., et al. Cytokine 51 (3) :217-226 (2010) Li, T., et al. Pharm Biol 48 (2) :161-165 (2010) Kunderfranco, P., et al. PLoS ONE (5), E10547 (2010) :

• Other Product Names:

  Protein C-ets-1, p54, ETS1, EWSR2

• Tested Applications:

  WB, IF, Flow

• Protein ID:

  119641

• Physical Properties:

  Liquid