ETS1 (phospho Thr38) Antibody

• Background:

  Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.

• NCBI Gene ID:

  2113

• Swiss Prot:

  P27577

• Accession Number:

  NP_035938.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  ETS1 (phospho Thr38) antibody was raised against a peptide sequence around phosphorylation site of threonine 38 (L-L-T (p) -P-S) derived from Human ETS1 .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  54 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of ETS1 only when phosphorylated at threonine 38.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

• Symbol:

  ETS1

• NCBI Official Name:

  V-ets avian erythroblastosis virus E26 oncogene homolog 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tsukasa Higuchi, Mol. Cell. Biol., May 2007; 27: 3353 - 3366.

• Background Reference 02:

  NK Bhat, PNAS, May 1990; 87: 3723.

• Background Reference 03:

  H Suzuki, PNAS, May 1995; 92: 4442.

• Background Reference 04:

  V Fafeur, Cell Growth Differ., Jun 1997; 8: 655.

• Other Product Names:

  P54, ETS1, ETS-1, C-ets-1 protein

• Tested Applications:

  WB, IHC, IF

• Protein ID:

  4885219

• Physical Properties:

  Liquid