MPPE1 Antibody

• Background:

  Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.

• NCBI Gene ID:

  65258

• Swiss Prot:

  Q53F39

• Accession Number:

  Q53F39

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MPPE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human MPPE1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MPPE1

• NCBI Official Name:

  Metallophosphoesterase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lohoff, F.W., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (3), 830-836 (2010) :

• Background Reference 02:

  Fujita, M., et al. Cell 139 (2) :352-365 (2009)

• Background Reference 03:

  Yosifova, A., et al.Affect Disord 117 (1-2), 87-97 (2009) :

• Background Reference 04:

  Fortna, A., et al. PLoS Biol. (7), E207 (2004) :

• Other Product Names:

  Metallophosphoesterase 1, 31--, Post-GPI attachment to proteins factor 5, MPPE1, PGAP5

• Tested Applications:

  WB

• Protein ID:

  215274110

• Physical Properties:

  Liquid