VLDLR Antibody [VLDLR/1337]

• Background:

  Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF) -like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

• NCBI Gene ID:

  7436

• Swiss Prot:

  P98155

• Host:

  Mouse

• Reactivity:

  Human, Rat

• Immunogen:

  A human recombinant partial protein from the C-terminal region was used as the immunogen for this VLDL Receptor antibody.

• Clonality:

  Monoclonal

• Clone:

  VLDLR/1337

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1

• Symbol:

  VLDLR

• NCBI Official Name:

  Very low density lipoprotein receptor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

• Tested Applications:

  WB, Flow, IF, IHC-P

• Physical Properties:

  Liquid