VLDLR Antibody

CAT: 0223-62-037Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-037Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq].
NCBI Gene ID
7436
Swiss Prot
P98155
Accession Number
P98155
Host
Rabbit
Reactivity
Human
Immunogen
This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-510 amino acids from the Central region of human VLDLR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
96 kDa
Fragment
Rabbit Ig
Symbol
VLDLR
NCBI Official Name
Very low-density lipoprotein receptor
NCBI Organism
Homo sapiens
Background Reference 01
Sakai, K., et al. Brain Res. 1276, 11-21 (2009)
Background Reference 02
Francis, P.J., et al. J. Med. Genet. 46 (5) :300-307 (2009)
Background Reference 03
Ananyeva, N.M., et al. Blood Coagul. Fibrinolysis 19 (6) :543-555 (2008)
Background Reference 04
Turkmen, S., et al. Eur. J. Hum. Genet. 16 (9) :1070-1074 (2008)
Other Product Names
Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR
Tested Applications
WB, IHC-P, Flow
Protein ID
1730111
Physical Properties
Liquid

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