VLDLR Antibody

• Background:

  The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq].

• NCBI Gene ID:

  7436

• Swiss Prot:

  P98155

• Accession Number:

  P98155

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-510 amino acids from the Central region of human VLDLR.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rb

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  96 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  VLDLR

• NCBI Official Name:

  Very low-density lipoprotein receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sakai, K., et al. Brain Res. 1276, 11-21 (2009)

• Background Reference 02:

  Francis, P.J., et al. J. Med. Genet. 46 (5) :300-307 (2009)

• Background Reference 03:

  Ananyeva, N.M., et al. Blood Coagul. Fibrinolysis 19 (6) :543-555 (2008)

• Background Reference 04:

  Turkmen, S., et al. Eur. J. Hum. Genet. 16 (9) :1070-1074 (2008)

• Other Product Names:

  Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  1730111

• Physical Properties:

  Liquid