AMACR / p504S Antibody [AMACR/1723]

• Background:

  AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

• NCBI Gene ID:

  23600

• Swiss Prot:

  Q9UHK6

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A recombinant human protein was used as the immunogen for the AMACR antibody.

• Clonality:

  Monoclonal

• Clone:

  AMACR/1723

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG

• Symbol:

  AMACR

• NCBI Official Name:

  Alpha-methylacyl-CoA racemase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR

• Tested Applications:

  WB, IHC-P, IF

• Physical Properties:

  Liquid