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CD1b Antibody [RIV12]

CAT: 0223-33-078Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-078Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.
NCBI Gene ID
910
Swiss Prot
P29016
Host
Mouse
Reactivity
Human
Immunogen
Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.
Clonality
Monoclonal
Clone
RIV12
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
CD1B
NCBI Official Name
CD1b molecule
NCBI Organism
Homo sapiens
Other Product Names
T-cell surface glycoprotein CD1b, CD1b, CD1B
Tested Applications
Flow, IF, Functional Assays
Physical Properties
Liquid

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