UBA52 Antibody

• Background :

  Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP) . Multiple processed pseudogenes derived from this gene are present in the genome.

• NCBI Gene ID :

  7311

• Swiss Prot :

  P62987

• Accession Number :

  P62987

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This UBA52 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the C-terminal region of human UBA52.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Pig, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  15 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  UBA52

• NCBI Official Name :

  Ubiquitin-60S ribosomal protein L40

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Memet, S. Biochem. Pharmacol. 72 (9) :1180-1195 (2006)

• Background Reference 02 :

  Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)

• Background Reference 03 :

  Foster, L.J., et al. J. Proteome Res. 5 (1) :64-75 (2006)

• Background Reference 04 :

  Hu, Y., et al. Mol. Cell Proteomics 4 (12) :2000-2009 (2005)

• Other Product Names :

  Ubiquitin-60S ribosomal protein L40, CEP52, Ubiquitin A-52 residue ribosomal protein fusion product 1, Ubiquitin, 60S ribosomal protein L40, UBA52, UBCEP2

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  302393718

• Physical Properties :

  Liquid