SIL1 Antibody

• Background :

  SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.

• NCBI Gene ID :

  64374

• Swiss Prot :

  Q9H173

• Accession Number :

  NP_071909

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIL1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Membrane

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SIL1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  49 kDa, 52 kDa

• Applications Notes :

  SIL1 antibody can be used for detection of SIL1 by ELISA at 1:62500. SIL1 antibody can be used for detection of SIL1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  SIL1

• NCBI Official Name :

  SIL1 nucleotide exchange factor

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Anttonen, A.K., (2005) Nat. Genet. 37 (12), 1309-1311.

• Other Product Names :

  SIL1, BAP, MSS, ULG5

• Tested Applications :

  ELISA, WB, IHC

• Protein ID :

  11968009

• Physical Properties :

  Liquid