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SIL1 Antibody

CAT: 0223-31-363Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-363Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
NCBI Gene ID
64374
Swiss Prot
Q9H173
Accession Number
NP_071909
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SIL1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
49 kDa, 52 kDa
Applications Notes
SIL1 antibody can be used for detection of SIL1 by ELISA at 1:62500. SIL1 antibody can be used for detection of SIL1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SIL1
NCBI Official Name
SIL1 nucleotide exchange factor
NCBI Organism
Homo sapiens
Background Reference 01
Anttonen, A.K., (2005) Nat. Genet. 37 (12), 1309-1311.
Other Product Names
SIL1, BAP, MSS, ULG5
Tested Applications
ELISA, WB, IHC
Protein ID
11968009
Physical Properties
Liquid

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