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SILV Antibody

CAT: 0223-30-232Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-30-232Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
NCBI Gene ID
6490
Swiss Prot
P40967
Accession Number
NP_008859
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SILV.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SILV antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
70 kDa
Applications Notes
SILV antibody can be used for detection of SILV by ELISA at 1:1562500. SILV antibody can be used for detection of SILV by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PMEL
NCBI Official Name
Premelanosome protein
NCBI Organism
Homo sapiens
Background Reference 01
Theos, A.C., (2006) Dev. Cell 10 (3), 343-354.
Other Product Names
SILV, D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M
Tested Applications
ELISA, WB, IHC
Protein ID
5902084
Physical Properties
Liquid

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