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TAF5L Antibody

CAT: 0223-31-261Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-261Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TAF5L functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
NCBI Gene ID
27097
Swiss Prot
O75529
Accession Number
NP_055224
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAF5L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10423 - Fetal Stomach Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TAF5L antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
66 kDa
Applications Notes
TAF5L antibody can be used for detection of TAF5L by ELISA at 1:62500. TAF5L antibody can be used for detection of TAF5L by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TAF5L
NCBI Official Name
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF) -associated factor, 65kDa
NCBI Organism
Homo sapiens
Background Reference 01
Ravnskjaer, K., (2007) EMBO J. 26 (12), 2880-2889 .
Other Product Names
TAF5L, PAF65B
Tested Applications
ELISA, WB
Protein ID
7657439
Physical Properties
Liquid

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