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TNFSF12 Antibody

CAT: 0223-31-142Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-142Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
NCBI Gene ID
8742
Swiss Prot
O43508
Accession Number
NP_003800
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFSF12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TNFSF12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
27 kDa, 37 kDa
Applications Notes
TNFSF12 antibody can be used for detection of TNFSF12 by ELISA at 1:12500. TNFSF12 antibody can be used for detection of TNFSF12 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TNFSF12
NCBI Official Name
Tumor necrosis factor (ligand) superfamily, member 12
NCBI Organism
Homo sapiens
Background Reference 01
Jin, L., et al., (2004) J. Invest. Dermatol. 122 (5), 1175-1179.
Other Product Names
TNFSF12, APO3L, DR3LG, TWEAK
Tested Applications
ELISA, WB
Protein ID
4507597
Physical Properties
Liquid

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