TNFSF14 Antibody

• Background:

  The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM) . This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

• NCBI Gene ID:

  8740

• Swiss Prot:

  O43557

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human TNFSF14

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Chemokines & Cytokines, Immunology, Innate Immunity

• Purification:

  Affinity purification

• Positive Control:

  Raji

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 30kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:1000 - 1:2000

• Symbol:

  TNFSF14

• Positive Control 2:

  LO2

• Positive Control 3:

  A-549

• Positive Control 4:

  293T

• Positive Control 5:

  THP-1

• NCBI Official Name:

  Tumor necrosis factor (ligand) superfamily, member 14

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Tumor necrosis factor superfamily member LIGHT, tumor necrosis factor receptor-like 2, tumor necrosis factor ligand superfamily, member 14, ligand for herpesvirus entry mediator, herpesvirus entry mediator A, delta transmembrane LIGHT, TR2, LTg, LIGHT, HVEML, CD258, tumor necrosis factor (ligand) superfamily, TNFSF14, UNQ391/PRO726

• Tested Applications:

  WB

• Physical Properties:

  Liquid