WARS2 Antibody

CAT: 0223-30-809Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-30-809Size:100 µL
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Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. WARS2 is the mitochondrial tryptophanyl-tRNA synthetase. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.
NCBI Gene ID
10352
Swiss Prot
Q9UGM6
Accession Number
NP_957715
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WARS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store WARS2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
24 kDa
Applications Notes
WARS2 antibody can be used for detection of WARS2 by ELISA at 1:312500. WARS2 antibody can be used for detection of WARS2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
WARS2
NCBI Official Name
Tryptophanyl tRNA synthetase 2, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Guo, L.T., (2007) Nucleic Acids Res. 35 (17), 5934-5943.
Other Product Names
WARS2, TrpRS
Tested Applications
ELISA, WB
Protein ID
41352700
Physical Properties
Liquid

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