FBXO7 Antibody

FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

25793

Q9Y3I1

NP_036311

Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXO7.

Unconjugated

Primary Antibodies

Apoptosis, Homeostasis

Antibody is purified by peptide affinity chromatography method.

Cat. No. 1219 - MCF7 Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FBXO7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

58 kDa

FBXO7 antibody can be used for detection of FBXO7 by ELISA at 1:1562500. FBXO7 antibody can be used for detection of FBXO7 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

FBXO7

F-box protein 7

Homo sapiens

Chang, Y.F., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1022-1026.

FBXO7, DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15

ELISA, WB

74229027