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TSHR Antibody

CAT: 0223-29-630Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-630Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5) .
NCBI Gene ID
7253
Swiss Prot
P16473
Accession Number
NP_000360
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TSHR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TSHR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
84 kDa
Applications Notes
TSHR antibody can be used for detection of TSHR by ELISA at 1:312500. TSHR antibody can be used for detection of TSHR by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TSHR
NCBI Official Name
Thyroid stimulating hormone receptor
NCBI Organism
Homo sapiens
Background Reference 01
Claus, M., (2005) Endocrinology 146 (12), 5197-5203.
Other Product Names
TSHR, LGR3, MGC75129, hTSHR-I, CHNG1
Tested Applications
ELISA, WB
Protein ID
64085121
Physical Properties
Liquid

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