RNF8 Antibody

CAT: 0223-29-182Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-182Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
NCBI Gene ID
9025
Swiss Prot
O76064
Accession Number
NP_003949
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RNF8 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
55 kDa, 51 kDa
Applications Notes
RNF8 antibody can be used for detection of RNF8 by ELISA at 1:312500. RNF8 antibody can be used for detection of RNF8 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RNF8
NCBI Official Name
Ring finger protein 8, E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Background Reference 01
Lehner, B. (2004) Genome Res. 14 (7), 1315-1323.
Other Product Names
RNF8, FLJ12013, KIAA0646, hRNF8
Tested Applications
ELISA, WB, IHC
Protein ID
4504867
Physical Properties
Liquid

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