RNF5 Antibody

• Background:

  The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.

• NCBI Gene ID:

  6048

• Swiss Prot:

  Q99942

• Accession Number:

  Q99942

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RNF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the Central region of human RNF5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  20 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RNF5

• NCBI Official Name:

  E3 ubiquitin-protein ligase RNF5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009) :

• Background Reference 02:

  Tcherpakov, M., et al. J. Biol. Chem. 284 (18) :12099-12109 (2009)

• Background Reference 03:

  Zhong, B., et al. Immunity 30 (3) :397-407 (2009)

• Background Reference 04:

  McKinnon, E., et al. Diabetes Obes Metab 11 SUPPL 1, 92-100 (2009) :

• Other Product Names:

  E3 ubiquitin-protein ligase RNF5, 632-, Protein G16, RING finger protein 5, Ram1 homolog, HsRma1, RNF5, G16, NG2, RMA1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74762702

• Physical Properties:

  Liquid