RNF5 Antibody

CAT: 0223-56-430Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-430Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
NCBI Gene ID
6048
Swiss Prot
Q99942
Accession Number
Q99942
Host
Rabbit
Reactivity
Human
Immunogen
This RNF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the Central region of human RNF5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Symbol
RNF5
NCBI Official Name
E3 ubiquitin-protein ligase RNF5
NCBI Organism
Homo sapiens
Background Reference 01
Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009) :
Background Reference 02
Tcherpakov, M., et al. J. Biol. Chem. 284 (18) :12099-12109 (2009)
Background Reference 03
Zhong, B., et al. Immunity 30 (3) :397-407 (2009)
Background Reference 04
McKinnon, E., et al. Diabetes Obes Metab 11 SUPPL 1, 92-100 (2009) :
Other Product Names
E3 ubiquitin-protein ligase RNF5, 632-, Protein G16, RING finger protein 5, Ram1 homolog, HsRma1, RNF5, G16, NG2, RMA1
Tested Applications
WB, IHC-P
Protein ID
74762702
Physical Properties
Liquid

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