RNF6 Antibody

CAT: 0223-25-816Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-25-816Size:100 µL
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Background
RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
NCBI Gene ID
6049
Swiss Prot
Q9Y252
Accession Number
NP_005968
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RNF6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
78 kDa
Applications Notes
RNF6 antibody can be used for detection of RNF6 by ELISA at 1:62500. RNF6 antibody can be used for detection of RNF6 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RNF6
NCBI Official Name
Ring finger protein (C3H2C3 type) 6
NCBI Organism
Homo sapiens
Background Reference 01
Tursun, B., (2005) Genes Dev. 19 (19), 2307-2319.
Other Product Names
RNF6, DKFZp686P0776, SPG2
Tested Applications
ELISA, WB
Protein ID
5174653
Physical Properties
Liquid

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