RNF2 Antibody

• Background:

  Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2) . Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

• NCBI Gene ID:

  6045

• Swiss Prot:

  Q99496

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RNF2 (NP_009143.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 38kDa

• Fragment:

  IgG

• Symbol:

  RNF2

• Positive Control 2:

  Jurkat

• Positive Control 3:

  U-937

• Positive Control 4:

  SH-SY5Y

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Mouse spleen

• NCBI Official Name:

  Ring finger protein 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RNF2, BAP1, DING, BAP-1, HIPI3, RING2, RING1B

• Tested Applications:

  WB, IHC, IF, IP, ChIP

• Physical Properties:

  Liquid