RNF2 Antibody

CAT: 0223-28-046Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-046Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2) . Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
NCBI Gene ID
6045
Swiss Prot
Q99496
Accession Number
NP_009143
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RNF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
38 kDa
Applications Notes
RNF2 antibody can be used for detection of RNF2 by ELISA at 1:312500. RNF2 antibody can be used for detection of RNF2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RNF2
NCBI Official Name
Ring finger protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Voncken, J.W., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2468-2473.
Other Product Names
RNF2, BAP1, DING, BAP-1, HIPI3, RING2, RING1B
Tested Applications
ELISA, WB
Protein ID
6005747
Physical Properties
Liquid

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