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PSMC5 Antibody

CAT: 0223-28-816Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-816Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
NCBI Gene ID
5705
Swiss Prot
P62195
Accession Number
NP_002796
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish, C. elegans, Drosophila
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PSMC5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
46 kDa
Applications Notes
PSMC5 antibody can be used for detection of PSMC5 by ELISA at 1:312500. PSMC5 antibody can be used for detection of PSMC5 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PSMC5
NCBI Official Name
Proteasome (prosome, macropain) 26S subunit, ATPase, 5
NCBI Organism
Homo sapiens
Background Reference 01
Inoue, T., et al., (2006) Biochem. Biophys. Res. Commun. 342 (3), 829-834.
Other Product Names
PSMC5, S8, p45, SUG1, SUG-1, TBP10, TRIP1, p45/SUG
Tested Applications
ELISA, WB
Protein ID
24497435
Physical Properties
Liquid

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