PSMD5 Antibody

• Background :

  The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.

• NCBI Gene ID :

  5711

• Swiss Prot :

  Q16401

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 255-504 of human PSMD5 (NP_005038.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  Affinity purification

• Positive Control :

  A-431

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 56kDa

• Fragment :

  IgG

• Symbol :

  PSMD5

• Positive Control 2 :

  BT-474

• Positive Control 3 :

  HeLa

• Positive Control 4 :

  Mouse liver

• Positive Control 5 :

  Rat liver

• NCBI Official Name :

  26S proteasome non-ATPase regulatory subunit 5

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  26S proteasome non-ATPase regulatory subunit 5, 26S protease subunit S5 basic, 26S proteasome subunit S5B, PSMD5, KIAA0072

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid