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TBX21 Antibody

CAT: 0223-28-638Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-638Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG) . Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
NCBI Gene ID
57765
Swiss Prot
Q9JKD8
Accession Number
NP_062380
Host
Rabbit
Reactivity
Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse TBX21.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
SP2/0 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TBX21 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
58 kDa
Applications Notes
TBX21 antibody can be used for detection of TBX21 by ELISA at 1:312500. TBX21 antibody can be used for detection of TBX21 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TBX21
NCBI Official Name
T-box 21
NCBI Organism
Mus musculus
Background Reference 01
Hirata, T., et al., (2006) Development 133 (8), 1433-1443.
Other Product Names
TBX21, TBT1, Tbet, Tblym
Tested Applications
ELISA, WB
Protein ID
247269497
Physical Properties
Liquid

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