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TBX2 Antibody

CAT: 0223-59-016Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-016Size:400 µL
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Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
NCBI Gene ID
6909
Swiss Prot
Q13207
Accession Number
Q13207
Host
Rabbit
Reactivity
Human
Immunogen
This TBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the Central region of human TBX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TBX2
NCBI Official Name
T-box transcription factor TBX2
NCBI Organism
Homo sapiens
Background Reference 01
Vance, K.W., et al. Mol. Biol. Cell 21 (15) :2770-2779 (2010)
Background Reference 02
Radio, F.C., et al. Am. J. Med. Genet.152A (8), 2061-2066 (2010) :
Background Reference 03
Kottgen, A., et al. Nat. Genet. 42 (5) :376-384 (2010)
Background Reference 04
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Other Product Names
T-box transcription factor TBX2, T-box protein 2, TBX2
Tested Applications
WB
Protein ID
294862490
Physical Properties
Liquid

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