BRD2 Antibody

• Background:

  BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control.

• NCBI Gene ID:

  6046

• Swiss Prot:

  P25440

• Accession Number:

  NP_005095

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BRD2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer, Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BRD2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  88 kDa

• Applications Notes:

  BRD2 antibody can be used for detection of BRD2 by ELISA at 1:312500. BRD2 antibody can be used for detection of BRD2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  BRD2

• NCBI Official Name:

  Bromodomain containing 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Pal, D.K., et al., (2003) Am. J. Hum. Genet. 73 (2), 261-270.

• Other Product Names:

  BRD2, FSH, NAT, RNF3, FSRG1, RING3, D6S113E

• Tested Applications:

  ELISA, WB

• Protein ID:

  4826806

• Physical Properties:

  Liquid