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CRSP6 Antibody

CAT: 0223-28-029Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-029Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
NCBI Gene ID
9440
Swiss Prot
Q9NVC6
Accession Number
NP_004259
Host
Rabbit
Reactivity
Human, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CRSP6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CRSP6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
73 kDa
Applications Notes
CRSP6 antibody can be used for detection of CRSP6 by ELISA at 1:12500. CRSP6 antibody can be used for detection of CRSP6 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MED17
NCBI Official Name
Mediator complex subunit 17
NCBI Organism
Homo sapiens
Background Reference 01
Wang, Q., et al., (2002) J. Biol. Chem. 277 (45), 42852-42858.
Other Product Names
CRSP6, CRSP6, CRSP77, DRIP80, TRAP80
Tested Applications
ELISA, WB, IHC
Protein ID
28558975
Physical Properties
Liquid

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