Products for Research Use Only
RegisterLogin

SMAD6 Antibody

CAT: 0223-27-669Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-27-669Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
NCBI Gene ID
4091
Swiss Prot
O43541
Accession Number
NP_005576
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction
Purification
Antibody is supplied as total IgG.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMAD6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
53 kDa
Applications Notes
SMAD6 antibody can be used for detection of SMAD6 by ELISA at 1:62500. SMAD6 antibody can be used for detection of SMAD6 by western blot at 0.5-1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SMAD6
NCBI Official Name
SMAD family member 6
NCBI Organism
Homo sapiens
Background Reference 01
Tsunobuchi, H., et al., (2004) Biophys. Res. Commun. 316 (3), 712-719.
Other Product Names
SMAD6, AOVD2, MADH6, MADH7, HsT17432
Tested Applications
ELISA, WB, IHC
Protein ID
92859871
Physical Properties
Liquid

Related Products

CatalogName
23-013SMAD2/SMAD3 Antibody
23-014SMAD2/SMAD3 Antibody
63-183SMAD4 Antibody
62-445Smad7 Antibody
57-106SMAD3 Antibody
27-476SMAD5 Antibody
27-475SMAD5 Antibody
27-474SMAD4 Antibody
14-031SMAD3 Antibody
46-383Smad9 Antibody

Alternative Products

CatalogName
70R-50030SMAD6 antibody

Popular Products