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SMAD3 Antibody

CAT: 0223-57-106Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-106Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
NCBI Gene ID
4088
Swiss Prot
P84022
Accession Number
P84022
Host
Rabbit
Reactivity
Human
Immunogen
This SMAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human SMAD3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
SMAD3
NCBI Official Name
Mothers against decapentaplegic homolog 3
NCBI Organism
Homo sapiens
Background Reference 01
Ge, Q., et al. J. Cell. Physiol. 225 (3) :846-854 (2010)
Background Reference 02
Lee, J., et al. J. Biol. Chem. 285 (34) :26618-26627 (2010)
Background Reference 03
Roder, C., et al. Childs Nerv Syst (2010) In press :
Background Reference 04
Valdes, A.M., et al. Arthritis Rheum. 62 (8) :2347-2352 (2010)
Other Product Names
Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3, SMAD3, MADH3
Tested Applications
WB, IHC-P, IF
Protein ID
51338669
Physical Properties
Liquid

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