Products for Research Use Only
RegisterLogin

PSMD4 Antibody

CAT: 0223-27-556Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-27-556Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid.
NCBI Gene ID
5710
Swiss Prot
P55036
Accession Number
NP_002801
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMD4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1207 - Raji Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PSMD4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
41 kDa
Applications Notes
PSMD4 antibody can be used for detection of PSMD4 by ELISA at 1:62500. PSMD4 antibody can be used for detection of PSMD4 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PSMD4
NCBI Official Name
Proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
NCBI Organism
Homo sapiens
Background Reference 01
Fujiwara, K., et al., (2004) J. Biol. Chem. 279 (6), 4760-4767.
Other Product Names
PSMD4, AF, ASF, S5A, AF-1, MCB1, Rpn10, pUB-R5
Tested Applications
ELISA, WB
Protein ID
5292161
Physical Properties
Liquid

Related Products

CatalogName
22-584PSMD5 Antibody
18-674PSMC4 Antibody
27-600PSMD14 Antibody
26-298PSMD8 Antibody
61-210PSME4 Antibody
60-676PSMD5 Antibody
13-800PSMD14 Antibody
18-814PSMD3 Antibody
18-436PSMD2 Antibody
16-596PSMD1 Antibody

Alternative Products

CatalogName
70R-19603PSMD4 antibody

Popular Products