PSMD3 Antibody

• Background :

  The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.

• NCBI Gene ID :

  5709

• Swiss Prot :

  O43242

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human PSMD3

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  Affinity purification

• Positive Control :

  BT-474

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 65kDa

• Fragment :

  IgG

• Symbol :

  PSMD3

• Positive Control 2 :

  SKOV3

• Positive Control 3 :

  293T

• NCBI Official Name :

  Proteasome 26S subunit, non-ATPase 3

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  P58, RPN3, S3, TSTA2, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit S3, proteasome (prosome, macropain) 26S subunit, non-ATPase, 3, proteasome subunit p58, tissue specific transplantation antigen 2

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid