INTS4 Antibody

• Background :

  INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2) .INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]) .

• NCBI Gene ID :

  92105

• Swiss Prot :

  Q96HW7

• Accession Number :

  NP_291025

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human INTS4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store INTS4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  108 kDa

• Applications Notes :

  INTS4 antibody can be used for detection of INTS4 by ELISA at 1:12500. INTS4 antibody can be used for detection of INTS4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  INTS4

• NCBI Official Name :

  Integrator complex subunit 4

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Baillat, D., (2005) Cell 123 (2), 265-276.

• Other Product Names :

  INTS4, INT4, MGC16733, MST093

• Tested Applications :

  ELISA, WB

• Protein ID :

  50086624

• Physical Properties :

  Liquid